Shortly after non-Indian travelers began to enter their territory, the Bannock began to attack them. During the 1840s thousands of U.S. settlers went west through Bannock territory along the Oregon Trail. Diseases brought by the newcomers, especially smallpox, were very harmful to the tribe. Around this time the Bannock population fell from about 2,000 to about 500. The settlers further angered the Bannock by slaughtering thousands of buffalo.
Bannock warriors continued to attack many of the wagon trains that crossed their land. The raids continued until 1869, when the United States government settled the Bannock and the Shoshone on the Fort Hall Reservation in present-day Idaho. Reservation life did not suit the Bannock, who were not farmers. The Bannock began to starve because the government did not give them food rations that it had promised.
Hungry and desperate, the Bannock, along with the Northern Paiute, revolted in 1878. The short Bannock War ended with the defeat of the Indians. The surviving Bannock were sent back to Fort Hall.
About 200 Bannock lived in the United States at the end of the 20th century. Most lived on their reservation, which they continue to share with the Shoshone. The Shoshone-Bannock (also known as the Sho-Bans) operate several businesses.